caiman matlab software (MathWorks Inc)
Structured Review

Caiman Matlab Software, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/caiman matlab software/product/MathWorks Inc
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "Molecular layer interneurons in the cerebellum encode for valence in associative learning"
Article Title: Molecular layer interneurons in the cerebellum encode for valence in associative learning
Journal: Nature Communications
doi: 10.1038/s41467-020-18034-2
Figure Legend Snippet: a go–no go task. Left: Two-photon imaging of a head-fixed mouse responding to odorants by licking on a water spout in response to the rewarded odorant in the go–no go task. Center: Scoring of decision-making. Right: time course of the trial. For water reward in Hit trials the animal must lick at least once in each of the two 2 s lick segments. b – d The panels in b and c show two-photon microscopy images of GCaMP6f fluorescence recorded from MLIs in a mouse proficient in the go–no go task (basal activity: before trial start, Hit trial: during reinforced odorant application). The color image in d shows the regions of interest identified using CaImAn software . e Pseudocolor plots displaying the average per trial Δ F / F time course for Hit (left panel) and CR (right panel) odorants for all ROIs in this example. GLM analysis involving time periods pre-odorant (1 s before odorant onset), odorant (last second during odorant application) and reinforcement (1.5 s after reinforcement), and different events (Hits, Miss, CR and FA) yielded significant differences between reinforcement and pre-odorant ( p < 0.001), between odorant and pre-odorant ( p < 0.001), and between all interactions between these two period pairs and all events ( p < 0.01, 2040 observations, 2028 degrees of freedom, n = 170 ROIs, 1 mouse, GLM F-statistic 234, p < 0.001). *Post-hoc ranksum p < pFDR = 0.048. f Neural ensemble activity. Black traces are the GCaMP6f fluorescence (Δ F / F ) time courses for a subset of the ROIs identified in the FOV in ( d ). This mouse was proficient (≥80% correct trials). Vertical lines: orange start and end of S+ odorant application, light blue is S−. The blue trace at the bottom shows the licks. All trials were Hits or CRs with the exception of the trial identified with the arrow that was a FA. Data shown in panels ( b – f ) are from one session (one mouse).
Techniques Used: Imaging, Microscopy, Fluorescence, Activity Assay, Software